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Shingrix: GSK Launches Herpes Zoster Vaccine in Malaysia
GlaxoSmithKline (GSK) has announced the launch of Shingrix, its highly effective vaccine for Herpes Zoster (HZ), commonly known as shingles, in Malaysia. This launch marks a significant step forward in the prevention of this painful and potentially debilitating disease in the country.
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Understanding Herpes Zoster (Shingles)
What is Herpes Zoster?
Herpes Zoster, or shingles, is a viral infection that causes a painful rash. The virus that causes shingles is the same virus that causes chickenpox, the varicella-zoster virus (VZV). After a person has chickenpox, the virus remains inactive in the body. For reasons that are not fully understood, the virus can reactivate later in life, causing shingles.
Who is at Risk of Shingles?
Anyone who has had chickenpox is at risk of developing shingles. However, the risk increases with age, with people over 50 being at higher risk. Other factors that can increase the risk of shingles include:
- Weakened immune system due to illness, medication, or stress
- Certain cancers, such as leukemia and lymphoma
- HIV/AIDS
Complications of Shingles
While most people recover from shingles within a few weeks, some experience complications, which can include:
- **Postherpetic neuralgia (PHN):** This is the most common complication of shingles, causing severe and long-lasting pain in the area where the rash occurred.
- **Vision loss:** Shingles can affect the eye, potentially leading to vision loss.
- **Neurological problems:** In rare cases, shingles can lead to neurological problems such as encephalitis (inflammation of the brain), meningitis (inflammation of the membranes surrounding the brain and spinal cord), or facial paralysis.
Shingrix: A New Era in Shingles Prevention
How Shingrix Works
Shingrix is a non-live, recombinant subunit vaccine that is given in two doses, two to six months apart. The vaccine works by exposing the body to a small amount of a protein found on the varicella-zoster virus. This triggers the immune system to produce antibodies that protect against future infection with the virus.
Efficacy and Safety of Shingrix
Clinical trials have shown that Shingrix is highly effective in preventing shingles and its complications. In adults aged 50 and over, Shingrix was over 90% effective in preventing shingles and over 85% effective in preventing PHN.
Shingrix has a favorable safety profile. The most common side effects reported in clinical trials were pain, redness, and swelling at the injection site. These side effects were generally mild to moderate and resolved within a few days.
Shingrix Availability and Target Population in Malaysia
The initial rollout of Shingrix in Malaysia will focus on adults aged 50 and over, the group at highest risk of developing shingles and experiencing complications.
Additionally, individuals aged 18 and over who are at increased risk of shingles due to underlying health conditions will also have access to the vaccine.
Addressing Concerns and FAQs About Shingrix
Is Shingrix Suitable for Everyone?
While Shingrix is generally safe and effective, it may not be suitable for everyone. It is essential to consult with a healthcare professional to determine if Shingrix is right for you. They will assess your medical history, allergies, and other factors to make the best recommendation for your individual needs.
What is the Recommended Vaccination Schedule?
Shingrix is given as two doses, two to six months apart. It is important to receive both doses to ensure optimal protection.
Can Shingrix Be Given with Other Vaccines?
Shingrix can be given at the same time as other vaccines, including the seasonal flu vaccine.
What is the Cost of Shingrix in Malaysia?
The cost of the Shingrix vaccine may vary depending on the healthcare provider and location. It is best to contact your doctor or clinic for specific pricing information.
Conclusion
The launch of Shingrix in Malaysia marks a significant advancement in the fight against shingles. This highly effective vaccine offers new hope for preventing this painful and potentially debilitating disease, particularly for those at higher risk. If you are 50 or older, or have other risk factors for shingles, talk to your healthcare provider about whether Shingrix is right for you.
Disclaimer: This article is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional for diagnosis and treatment recommendations.
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